The books in which the series are collected (as opposed to the individual monthly or weekly magazines, in which the stories are typically first published, which, when they're gone, they're gone) are usually kept in print (that is, reprinted), at least for the most popular series, for a good many years.
I have here, for instance, a copy of volume 1 of the pocket edition of 'Urusei Yatsura'. It's on its third printing already, and the first print run came out only a year ago. And these are stories from 1978, which have been continuously available, in one edition or another, ever since then.
[I seem to remember seeing a Ranma 1/2 book, one of the earlier ones, which was already on its 60th printing, which would mean a new print run would have come out, on the average, every two months for the past 10 years!]
For more obscure manga I assume it will be like for more obscure books, records, etc., that is, the publishers may not feel the need to reprint them. But the series that have reached 'classic' status will always be kept available, I think, in one form or another.
Nausicaa is definitely one of those 'classic' series, available, currently, in two editions, the 'cheap' one in 7 volumes (the earliest of which have undergone already countless reprints, since the mid-eighties) and a hugely expensive one in two hardbound volumes which I plan to purchase as soon as I win the lottery...